Gene name:
ZEB2 (HRIHFB2411;KIAA0569;SIP1;ZFHX1B;ZFX1B) ;
Protein name:
Zinc finger E-box-binding homeobox 2 ;
Alternative:
Zinc finger homeobox protein 1b ;Smad-interacting protein 1 (SMADIP1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Binds activated SMAD1, activated SMAD2 and activated SMAD3; binding with SMAD4 is not detected (By similarity). Interacts with CBX4 and CTBP1.
Function:
Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters. Represses transcription of E-cadherin.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MKQPIMADGP | RCKRRKQANP | RRKNVVNYDN | VVDTGSETDE | EDKLHIAEDD |
100:
GIANPLDQET | SPASVPNHES | SPHVSQALLP | REEEEDEIRE | GGVEHPWHNN |
150:
EILQASVDGP | EEMKEDYDTM | GPEATIQTAI | NNGTVKNANC | TSDFEEYFAK |
200:
RKLEERDGHA | VSIEEYLQRS | DTAIIYPEAP | EELSRLGTPE | ANGQEENDLP |
250:
PGTPDAFAQL | LTCPYCDRGY | KRLTSLKEHI | KYRHEKNEEN | FSCPLCSYTF |
300:
AYRTQLERHM | VTHKPGTDQH | QMLTQGAGNR | KFKCTECGKA | FKYKHHLKEH |
350:
LRIHSGEKPY | ECPNCKKRFS | HSGSYSSHIS | SKKCIGLISV | NGRMRNNIKT |
400:
GSSPNSVSSS | PTNSAITQLR | NKLENGKPLS | MSEQTGLLKI | KTEPLDFNDY |
450:
KVLMATHGFS | GTSPFMNGGL | GATSPLGVHP | SAQSPMQHLG | VGMEAPLLGF |
500:
PTMNSNLSEV | QKVLQIVDNT | VSRQKMDCKA | EEISKLKGYH | MKDPCSQPEE |
550:
QGVTSPNIPP | VGLPVVSHNG | ATKSIIDYTL | EKVNEAKACL | QSLTTDSRRQ |
600:
ISNIKKEKLR | TLIDLVTDDK | MIENHNISTP | FSCQFCKESF | PGPIPLHQHE |
650:
RYLCKMNEEI | KAVLQPHENI | VPNKAGVFVD | NKALLLSSVL | SEKGMTSPIN |
700:
PYKDHMSVLK | AYYAMNMEPN | SDELLKISIA | VGLPQEFVKE | WFEQRKVYQY |
750:
SNSRSPSLER | SSKPLAPNSN | PPTKDSLLPR | SPVKPMDSIT | SPSIAELHNS |
800:
VTNCDPPLRL | TKPSHFTNIK | PVEKLDHSRS | NTPSPLNLSS | TSSKNSHSSS |
850:
YTPNSFSSEE | LQAEPLDLSL | PKQMKEPKSI | IATKNKTKAS | SISLDHNSVS |
900:
SSSENSDEPL | NLTFIKKEFS | NSNNLDNKST | NPVFSMNPFS | AKPLYTALPP |
950:
QSAFPPATFM | PPVQTSIPGL | RPYPGLDQMS | FLPHMAYTYP | TGAATFADMQ |
1000:
QRRKYQRKQG | FQGELLDGAQ | DYMSGLDDMT | DSDSCLSRKK | IKKTESGMYA |
1050:
CDLCDKTFQK | SSSLLRHKYE | HTGKRPHQCQ | ICKKAFKHKH | HLIEHSRLHS |
1100:
GEKPYQCDKC | GKRFSHSGSY | SQHMNHRYSY | CKREAEEREA | AEREAREKGH |
1150:
LEPTELLMNR | AYLQSITPQG | YSDSEERESM | PRDGESEKEH | EKEGEDGYGK |
1200:
LGRQDGDEEF | EEEEEESENK | SMDTDPETIR | DEEETGDHSM | DDSSEDGKME |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Zinc finger E-box-binding homeobox 2
ELISA Kit for Human Zinc finger E-box-binding homeobox 2
CLIA Kit for Human Zinc finger E-box-binding homeobox 2
CLIA Kit for Human Zinc finger E-box-binding homeobox 2
Polyclonal Antibody for Human Zinc finger E-box-binding homeobox 2
Polyclonal Antibody for Human Zinc finger E-box-binding homeobox 2
Monoclonal Antibody for Human Zinc finger E-box-binding homeobox 2
Monoclonal Antibody for Human Zinc finger E-box-binding homeobox 2
Protein for Human Zinc finger E-box-binding homeobox 2
Protein for Human Zinc finger E-box-binding homeobox 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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